COEXISTENCE OF KAPOSIFORM HEMANGIOENDOTHELIOMA AND CAPILLARY MALFORMATION: MORE THAN A COINCIDENCE? TWO CASE REPORTS

Coexistence of kaposiform hemangioendothelioma and capillary malformation: More than a coincidence? Two case reports

The coexistence of kaposiform hemangioendothelioma (KHE) and Heat Packs capillary malformation (CM) is quite rare, and few relevant studies can be found to confirm whether this phenomenon is accidental.We diagnosed and treated two such patients, revealing interesting phenomena associated with the development of vascular diseases.These cases offer t

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N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain.

Flt is one of the cell surface VEGF receptors which can be cleaved to release an N-terminal extracellular fragment which, like alternately transcribed soluble Flt1 (sFlt1), can antagonize Flu Support the effects of VEGF.In HUVEC and in HEK293 cells where Flt1 was expressed, metalloprotease inhibitors reduced Flt1 N-terminal cleavage.Overexpression

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